Dihydromyricetin (DHM) – also known as ampelopsin – is a type of flavonoid known to have anti-diabetic, anti-inflammatory, antimicrobial, and anti-oxidative properties, while possessing the added benefits of being able to relieve hangover symptoms, liver damage, and withdrawal symptoms. The compound occurs naturally and may be found in the Oriental Raisin Tree located primarily in Asia.
Though it is widely used in Traditional Eastern medicine, it is absent in western medicine. One reason may be that it is not seen as financially viable to conduct scientific testing for patenting on natural compounds when compared to that of synthetic compounds. However, the effects of DHM on alcohol intoxication were explored in rats. In these studies, the compound was found to have a significant effect on the level of intoxication experienced by the rats. The rate at which alcohol was metabolized increased by almost fifteen times the rate of those rats that did not receive DHM. The latter group also experienced more severe withdrawal symptoms and hangovers.
Benzodiazepines – widely used to combat anxiety symptoms – are the primary drug of choice to ease alcohol withdrawal symptoms, while posing the risk of side effects and dependence. As it turns out, DHM acts on the very same gamma-aminobutyric acid (GABA) receptors that benzodiazepines do, however, their use is limited due to the fact that their suitability hasn’t been thoroughly explored in humans, at least, not here in the West. Given the success observed in the use of DHM to combat the side effects of alcohol in rats, it is assumed that it would be just as successful, if not more, in treating alcohol use disorders in humans, with few, to no side effects.
In considering the personal use of DHM, perform your due diligence before deciding if this route is right for you.Back to Blog